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Post doc in basic mechanisms in primary immunodeficiencies 981676

A Three-year position as postdoc at the Department of Biomedicine, Aarhus University, is open for appointment from October 1, 2018 or soon thereafter.

The innate immune system is the first barriers to infections. Patients with genetic defects in the innate immune system exhibit selective susceptibility to infections. We are using gene-modified mouse strains harboring disease-causing mutations identified in patients, and mouse models for virus infections to uncover the mechanisms leading to infectious diseases in genetically predisposed individuals. The work will include a panel of cutting-edge methods including immunohistochemistry, laser capture micro dissection, and RNA sequencing. This will be combined with in vitro work, based on e.g. human stem cell-derived cells.

We are looking for a post-doctoral scientist with strong interest in infection pathogenesis. You will be working with mouse models for viral infections with focus on the innate immune response. Applicants with previous documented experience with advanced animal science, cutting-edge methods used in this field, or iPSC work related to immunology will be preferred. You should have solid analytical thinking, creativity and a visible publication record. In addition to the primary project, the successful applicant is expected to contribute intellectually to other ongoing and related projects in the group. We offer a dynamic, ambitious, and productive environment for a young scientist, and a good platform for a future career in frontline research.

Recent publications from the group:
Iversen MB et al. An Innate antiviral pathway acting before interferons at epithelial surfaces. Nat Immunol. 2016; 17:150-8.

Reinert LS et al. Sensing of HSV1 by the cGAS-STING pathway in microglia orchestrates antiviral defense in the CNS. Nat Commun. 2016; 7:13348.

Ogunjimi et al. Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections. J Clin Invest. 2017; 127:3543.

For further information, please contact professor Søren Riis Paludan (email: srp@biomed.au.dk).
Required qualifications

Appointment as a postdoc requires academic qualifications at PhD level.

Formalities and references

  • Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
  • The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
  • Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.
  • Further information on qualification requirements and job description can be found in the Memorandum on Job Structure for Academic Staff at Danish Universities (in Danish).
  • Application

    Applications must be accompanied by a CV, diploma, a list of publications as well as a teaching portfolio. Template for applicant - postdoc must be completed and uploaded under Other information to consider. A maximum of five of the publications of greatest relevance to the job must be submitted.

    Further information on the application and supplementary materials may be found in the facultys Guidelines for applicants for academic positions and Aarhus Universitys Guidelines on the use of teaching portfolios.

    The assessment committee may decide to include non-submitted material in its assessment. In such cases, the applicant will be informed and obliged to submit material, unless the application is withdrawn.

    Applications submitted through channels other than the online application form below or applications which are not received by the application deadline will not be considered.

    All interested candidates are encouraged to apply, regardless of their personal background.


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