Site visit at Department of Forensic Medicine
Info about event
Department of Forensic Medicine, Palle Juul Jensen’s Boulevard 43, 8200 Aarhus N (Entrance D2, Aarhus University Hospital)
The Food and Nutrition Network invites all members to join the first network site visit hosted by the Department of Forensic Medicine.
At the site visit, you will hear researchers from the departments Bioanalytical Research Unit present their research followed by a guided tour round the department. You will also have the chance to meet other network members over a cup of coffee and learn about the possibilities for collaborating with Bioanalytical Research Unit.
Information about the bioanalytical research unit is available at the Bioanalytical Unit website. The site visit is the first in a series of events where you will have the chance to meet and network with other Food and Nutrition Network members.
Date and time: September 15, 2021 @14:30 – 16:00
Location: Department of Forensic Medicine, Palle Juul Jensen’s Boulevard 43, 8200 Aarhus N (Entrance D2, Aarhus University Hospital)
Registration: at https://events.au.dk/sitevisitforensicmedicine2021 no later than September 9, 2021
Meet Jørgen Bo Hasselstrøm:
During the last decade more than 800 new psychoactive substances has entered the illegal drug market in Europe. Detecting these new structures in biological samples on a daily basis calls for versatile, sensitive and robust techniques. We have a well‐equipped laboratory with different chromatography and mass spectrometry systems ((HS)‐GC‐MS, UPLC‐MS/MS and UPLC‐QTOF) available and have developed several innovative analytical methods utilizing these systems. Our approach and experience has enabled us to solve many different analytical challenges for other research groups within the field of qualitatively and/or quantitatively measurement of small molecules (both endo‐ and exogenous) in complex matrices.
Meet Steffen Sinning:
Steffen Sinning’s group is interested in how membrane proteins are modulated by medication, drugs of abuse and lipids. We have established methods for activity and binding studies of various transport proteins and receptors in live cells as well as methods for assessing regulatory protein-protein interactions using isotope-, fluorescence or luminescence-based assay modalities. These methods can be used in conjunction with genetic manipulation of target proteins (mutation, fusion proteins etc.) to elucidate molecular mechanisms of ligands on their targets and the role of membrane lipids in the function of membrane proteins.
Meet Mogens Johannsen:
The Johannsen research group is mainly interested in how lipid and carbohydrate metabolism impact on biological aging at the molecular level. For this we use chemical probes to elucidate proteins that are prone to formation of advanced glycation endproducts, as well as non-enzymatic acylation e.g. acetylation. Secondarily, we conduct functional follow-up studies to elucidate a potential physiological relevance of the modifications. In other projects, we use chemical genetics (cell based screening) to discover novel proteins and small molecules regulating lipid metabolism and ketogenesis. Finally, untargeted metabolomics is broadly used to get insight into human metabolism.