According to the newly appointed doctor, Mikkel Bo Brent from the Department of Biomedicine, osteoporosis is a highly underdiagnosed disease, because it does not present with any obvious symptoms on its own. Patients are unaware that their bone mass is low – the first symptom is often complex and painful fractures, after which there is a significant need for potent and effective medical treatment.

“My higher doctoral dissertation focuses on how different types of bone loss in humans can be studied in animal models, allowing my colleagues and me to develop new and more effective treatment options for patients with osteoporosis,” says Mikkel Bo Brent.

He is conducting research into treatment combinations with medications and new molecules that can simultaneously increase bone and muscle mass. Additionally, he is exploring the possibility of repurposing medications that are already approved for the treatment of other diseases than osteoporosis.

“In general, my research contributes to a better understanding of bone loss and opens the door for future clinical trials of new treatment strategies and drug combinations for osteoporosis,” says Mikkel Bo Brent.

He uses preclinical animal models for bone diseases in humans, employs advanced 3D bone scanning technologies, and investigates bone cells using artificial intelligence.

Contact

MD, PhD and DMSc Mikkel Bo Brent
Aarhus University, Department of Biomedicine
Phone: +45 26 85 70 50
Email: mbb@biomed.au.dk

This text is based on machine translation.