Globally, 3 out of 5 persons lose their lives to chronic inflammatory conditions, such as diabetes, cardiovascular disorders, cancer, chronic respiratory diseases, skin diseases, renal diseases and obesity. Inflammatory diseases are the most prevailing cause of death worldwide and the numbers keep rising.

The network focuses on reducing the burden of infectious and inflammatory diseases caused by pathogens, damaged cells, toxic compounds or radiation in order to develop new diagnostic and treatment technologies.

As a society, we need more knowledge about the correlation between e.g. inflammation and development of cancer, about biomarkers and about molecular mechanisms of autoimmunity in e.g. rheumatological conditions - not to mention chronic mucosal inflammation. In the inflammation network we collaborate interdisciplinearily in order to find answers.

We comprise a wide range of researchers with interest in diagnostic methods, epidemiological data, inflammatory markers and intracellular pathways, understanding of cell population and tissue structures, among others.


Subject-specific programmes for PhD students

The subject-specific PhD programme in inflammation at Aarhus University, Health, offers an in-depth, multidisciplinary study of inflammation's role in diseases and prevention, addressing its significant role in both non-communicable diseases (NCD) and infections.

For more information about the subject-specific programmes: Subject-specific programmes, Graduate School of Health (au.dk).


Paper of the month

Paper of the month, June 2025, is presented by Professor Thomas Vorup-Jensen, Department of Biomedicine.

"Osteoclast-like multinucleated giant cells reinforce polycaprolactone grafts" H.B Ejnarsson, T. Vorup-Jensen et al, Frontiers in Immunology, Volume 16,-2025

Read the paper: Frontiers | Osteoclast-like multinucleated giant cells reinforce polycaprolactone grafts

Why is this paper important?

Interdisciplinary research is usually hailed as one of only a few ways to deal with the complexity of modern-day science. But what will an interdisciplinary paper in immunology actually look like? Here, we present a highly interdisciplinary paper focusing on the innate immune system's interaction with plastic polymers that mat play a role as implant material in reconstructive cranial surgery, for instance, in the scull. To handle the reaction between monocytes and the polycaprolactone polymer material, we used classic techniques such fluorescent microscopy and ELISA-like assays to follow CD18 receptor shedding. However, more advanced techniques such as dynamic mechanical analysis using sound waves to probe mass changes in the polymer also proved necessary. Our data points to rich source of information extending insights on innate immune cells capabilities



A video about The Inflammation Network

Contact

Anja P. Einholm

Network Coordinator


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