American health authority grants DKK 14 million to Aarhus-Harvard collaboration

Together with a Danish-American research group, medical doctor and PhD Mads Dam Lyhne from the Department of Clinical Medicine and Aarhus University Hospital will examine whether oxygen therapy can lower blood pressure in the lungs of patients with acute pulmonary embolisms.

In addition to Mads Dam Lyhne (pictured), the research group in Aarhus consists of Asger Andersen, a clinical associate professor at the Department of Clinical Medicine and cardiologist at Aarhus University Hospital.
In addition to Mads Dam Lyhne (pictured), the research group in Aarhus consists of Asger Andersen, a clinical associate professor at the Department of Clinical Medicine and cardiologist at Aarhus University Hospital. Photo: Daniel Schultz Madsen

In collaboration with doctors and researchers at Harvard Medical School and Massachusetts General Hospital (MGH) in Boston, researchers at Aarhus University and Aarhus University Hospital have applied for a major grant at the National Institute of Health (NIH) in the United States. The NIH has chosen to support the project with approx. DKK 14 million.

"The project is centred on using oxygen to treat acute blood clots in lungs. The blood clots cause the blood pressure in lungs to increase so much that it can lead to acute heart failure and death," says medical doctor and PhD Mads Dam Lyhne.

The project builds on Mads Dam Lyhne's PhD, where he used pigs to demonstrate that oxygen therapy can reduce blood pressure in the lungs very effectively.

The Danish-American research group will now study the effect of the treatment on patients with acute blood clots in their lungs. The researchers will also conduct further experiments on pigs to investigate the mechanisms behind the effects of oxygen treatment. The project is expected to take four years.

This coverage is based on press material from Aarhus University Hospital.

Contact

Medical doctor and PhD Mads Dam Lyhne
Aarhus University, Department of Clinical Medicine and
Aarhus University Hospital, Department of Anaesthesiology and Intensive Care
Mobile: +45 20 45 04 86
Email: mads.dam@clin.au.dk