Publications

Keep up with the latest research at the Faculty of Health.

The list below presents publications from the Faculty of Health, with the most recent at the top.

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Sanchez-Guajardo, V., Annibali, A., Jensen, P. H. & Romero-Ramos, M. (2013). α-Synuclein Vaccination Prevents the Accumulation of Parkinson Disease-Like Pathologic Inclusions in Striatum in Association With Regulatory T Cell Recruitment in a Rat Model. Journal of Neuropathology and Experimental Neurology, 72(7), 624-45. https://doi.org/10.1097/NEN.0b013e31829768d2

Christiansen, J. R., Olesen, M. N., Otzen, D. E., Romero-Ramos, M. & Sanchez-Guajardo, V. (2016). α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology. Journal of Neuroinflammation, 13(1), Article 74. https://doi.org/10.1186/s12974-016-0532-8

Sahin, C., Kjær, L., Christensen, M. S., Nedergaard Pedersen, J., Christiansen, G., Pérez, A.-M. W., Moller, I. M., Enghild, J., Pedersen, J. S., Larsen, K. & Otzen, D. E. (2018). α-synucleins from animal species show low fibrillation propensities and weak oligomer membrane disruption. Biochemistry, 57(34), 5145-5158. https://doi.org/10.1021/acs.biochem.8b00627

Halliday, G. M., Ophof, A., Broe, M., Jensen, P. H., Kettle, E., Fedorow, H., Cartwright, M. I., Griffiths, F. M., Shepherd, C. E. & Double, K. L. (2005). α-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson’s disease. Brain, 128, 2654-2664.

da Silva, I. S., Cardoso, A. R., Reimer, L., König, A., van Riesen, C., Outeiro, T. F., Jensen, P. H. & Sales, M. G. F. (2025). α-Synuclein plastic antibody applied to monitor monomeric structures and discriminate aggregated forms in human CSF. Biosensors and Bioelectronics, 268, 116880. Article 116880. https://doi.org/10.1016/j.bios.2024.116880

Ghanem, S. S., Majbour, N. K., Vaikath, N. N., Ardah, M. T., Erskine, D., Jensen, N. M., Fayyad, M., Sudhakaran, I. P., Vasili, E., Melachroinou, K., Abdi, I. Y., Poggiolini, I., Santos, P., Dorn, A., Carloni, P., Vekrellis, K., Attems, J., McKeith, I., Outeiro, T. F. ... El-Agnaf, O. M. A. (2022). α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity. Proceedings of the National Academy of Sciences (PNAS), 119(15), Article e2109617119. https://doi.org/10.1073/pnas.2109617119

Delaidelli, A., Richner, M., Jiang, L., van der Laan, A., Bergholdt Jul Christiansen, I., Ferreira, N., Nyengaard, J. R., Vægter, C. B., Jensen, P. H., Mackenzie, I. R., Sorensen, P. H. & Jan, A. (2021). α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response. Acta Neuropathologica Communications, 9(1), Article 105. https://doi.org/10.1186/s40478-021-01209-3

Stokholm, K., Thomsen, M. B., Phan, J. A., Møller, L. K., Bay-Richter, C., Christiansen, S. H., Woldbye, D. P. D., Romero-Ramos, M. & Landau, A. M. (2021). α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease. Biomedicines, 9(12), Article 1876. https://doi.org/10.3390/biomedicines9121876

Jiang, L. (2022). α-synuclein in Parkinson’s disease: mechanistic significance of PLK-2/GSK-3β and Nrf2 antioxidant response. [PhD thesis, Aarhus University].

Lindersson, E., Højrup, P., Gai, W.-P., Locker, D., Martin, D. & Jensen, P. H. (2004). α-synuclein filaments bind the transcriptional activator HMGB-1. J Neuroreport, 15, 2735-2739.

Febbraro, F., Giorgi, M., Caldarola, S., Loreni, F. & Romero-Ramos, M. (2012). α-Synuclein expression is modulated at the translational level by iron. NeuroReport, 23(9), 576-80. https://doi.org/10.1097/WNR.0b013e328354a1f0

Jensen, P. H. & Gai, W. P. (2001). α-synuclein axonal transport, ligand interaction and neurodegeneration. Advances in Experimental Medicine and Biology, 487, 129-134.

Kragh, C. L., Lund, L. B., Febbraro, F., Hansen, H. D., Gai, W. P., Richter-Landsberg, C. & Jensen, P. H. (2009). α-synuclein aggregation and Ser129 phosphorylation dependent cell death in oligodendroglial cells. Journal of Biological Chemistry, 284, 10211-10222.

Richelsen, B. & Sørensen, N. S. (1987). α₂- and β-adrenergic receptor binding and action in gluteal adipocytes from patients with hypothyroidism and hyperthyroidism. Metabolism, 36(11), 1031-1039. https://doi.org/10.1016/0026-0495(87)90022-9

Richelsen, B. & Pedersen, O. (1985). α₂-adrenergic binding and action in human adipocytes. Comparison between binding to plasma membrane preparations and to intact adipocytes. European Journal of Pharmacology, 119(1-2), 101-112. https://doi.org/10.1016/0014-2999(85)90327-9

Wikberg-Matsson, A. & Simonsen, U. (2001). α_2A-Adrenoceptors mediate the potent vasoconstriction induced by brimonidine in porcine ciliary arteries. Invest. Opthalmol. Vis. Sci., 42, 2049-2055.

van Rijt, W. G., Secher, N., Keller, A. K., Møldrup, U., Chynau, Y., Ploeg, R. J., van Goor, H., Nørregaard, R., Birn, H., Frøkiaer, J., Nielsen, S., Leuvenink, H. G. D. & Jespersen, B. (2014). α-Melanocyte Stimulating Hormone Treatment in Pigs Does Not Improve Early Graft Function in Kidney Transplants from Brain Dead Donors. PLoS One, 9(4), e94609. https://doi.org/10.1371/journal.pone.0094609

Mahía, A., Kiib, A. E., Nisavic, M., Svenningsen, E. B., Palmfeldt, J. & Poulsen, T. B. (2023). α-Lactam Electrophiles for Covalent Chemical Biology. Angewandte Chemie - International Edition, 62(26), Article e202304142. https://doi.org/10.1002/anie.202304142

Skals, M. G., Jørgensen, N. R., Leipziger, J. G. & Prætorius, H. (2009). α-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis. Proceedings of the National Academy of Sciences (PNAS), 106, 4030-4035.

Johnsen, N., Hamilton, A. D. M., Greve, A. S., Christensen, M. G., Therkildsen, J. R., Wehmöller, J., Skals, M. & Praetorius, H. A. (2019). α-Haemolysin production, as a single factor, causes fulminant sepsis in a model of Escherichia coli-induced bacteraemia. Cellular Microbiology, 21(6), Article e13017. https://doi.org/10.1111/cmi.13017

Christensen, H. M., Frystyk, J., Faber, J., Schou, M., Flyvbjerg, A., Hildebrandt, P., Raymond, I. E., Klausen, T. W. & Kistorp, C. M. N. (2012). α-Defensins and outcome in patients with chronic heart failure. European Journal of Heart Failure, 14(4), 387-94. https://doi.org/10.1093/eurjhf/hfs021

Doganli, C., Beck, H. C., Ribera, A. B., Oxvig, C. & Lykke-Hartmann, K. (2013). α3Na+/K+-ATPase deficiency causes brain ventricle dilation and abrupt embryonic motility in zebrafish. Journal of Biological Chemistry, 288, 8862-8874. https://doi.org/10.1074/jbc.M112.421529

Cavallaro, U., Nykjær, A., Nielsen, M. S. & Soria, M. R. (1995). α2-macroglobulin receptor mediates binding and cytotoxicity of plant ribosome-inactivating proteins. FEBS journal, 232, 165-171.

Lillethorup, T. P., Iversen, P., Wegener, G., Doudet, D. J. M. & Landau, A. M. (2015). α2-adrenoceptor binding in Flinders-sensitive line compared with Flinders-resistant line and Sprague-Dawley rats. Acta Neuropsychiatrica (Print), 1-8. https://doi.org/10.1017/neu.2015.24

Nørholt, S. E., Sköldstam, J., Blomlöf, J., Karunahara, S. & Pedersen, T. K. (2022). Zygomatic repositioning and Le Fort II distraction with intraoral devices in Apert syndrome: A case report: A case report. Journal of Cranio-Maxillofacial Surgery, 50(4), 364-370. https://doi.org/10.1016/j.jcms.2022.02.010

Krieger, J. (2021). Zurück in die Zukunft? Südwest Presse, 77(159), 15. https://www.tagblatt.de/Nachrichten/Zurueck-in-die-Zukunft-509332.html

Frøkiær, J. & Eskild-Jensen, A. (2003). Zur klinishen Wertigkeit der Nierenfunktionsszintigraphie bei pränatal diagnostizierten renalen Abflussstörungen. Der Nuklearmediziner, 26, 1-5.

Simonsen, U., Laursen, B. E. & Petersen, J. S. (2008). ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries. British Journal of Pharmacology, 153(6), 1185-94. https://doi.org/10.1038/sj.bjp.0707688

Thim, T., Maeng, M., Kaltoft, A., Jensen, L. O., Tilsted, H.-H., Hansen, P. R., Kelbaek, H., Thayssen, P., Ravkilde, J., Madsen, M., Sørensen, H. T., Thuesen, L. & Lassen, J. F. (2012). Zotarolimus-eluting vs. sirolimus-eluting coronary stents in patients with and without acute coronary syndromes: a SORT OUT III substudy. European Journal of Clinical Investigation, 42(10), 1047-1054. https://doi.org/10.1111/j.1365-2362.2012.02692.x

Mæng, M., Holm, N. R., Kaltoft, A., Jensen, L. O., Hansen, H.-H. T., Thuesen, L. & Lassen, J. F. (2010). Zotarolimus-eluting versus sirolimus-eluting coronary stent implantation. Interventional Cardiology, 2(6), 208-12. https://doi.org/10.2217/ica.10.72

Raungaard, B., Jensen, L. O., Tilsted, H.-H., Christiansen, E. H., Maeng, M., Terkelsen, C. J., Krusell, L. R., Kaltoft, A., Kristensen, S. D., Bøtker, H. E., Thuesen, L., Aarøe, J., Jensen, S. E., Villadsen, A. B., Thayssen, P., Veien, K. T., Hansen, K. N., Junker, A., Madsen, M. ... for the Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) (2015). Zotarolimus-eluting durable-polymer-coated stent versus a biolimus-eluting biodegradable-polymer-coated stent in unselected patients undergoing percutaneous coronary intervention (SORT OUT VI): a randomised non-inferiority trial. Lancet, 385(9977), 1527–1535. https://doi.org/10.1016/S0140-6736(14)61794-3

Drewes, A. M., Andreasen, A., Jennum, P. & Nielsen, K. D. (1991). Zopiclone in the treatment of sleep abnormalities in fibromyalgia. Scandinavian Journal of Rheumatology, 20(4), 288-93.

Jõgi, N. O., Svanes, C., Siiak, S. P., Logan, E., Holloway, J. W., Igland, J., Johannessen, A., Levin, M., Real, F. G., Schlunssen, V., Horsnell, W. G. C. & Bertelsen, R. J. (2018). Zoonotic helminth exposure and risk of allergic diseases: A study of two generations in Norway. Clinical and Experimental Allergy, 48(1), 66-77. https://doi.org/10.1111/cea.13055

Jogi, N. O., Siiak, S. P., Logan, E., Schlunssen, V., Svanes, C., Holloway, J. W., Bertelsen, R. J. & Horsnell, W. (2017). Zoonotic exposure to helminths is associated with allergic sensitization in a Norwegian population. European Respiratory Journal, 50(Suppl 61), Article PA4055. https://doi.org/10.1183/1393003.congress-2017.PA4055

Agger, J. F., Miazi, O. F., Christoffersen, AB., Agerholm, J. S., Villumsen, S., Kantsø, B., Bosnjak, E. & Nielsen, H. I. (2011). Zoonotic aspects of Coxiella burnetii antibody positivity between dairy cattle herds and their farmers. Poster session presented at International Meeting on Emerging Diseases and Surveillance, Wien, Austria.

Agger, J. F., Miazi, O. F., Christoffersen, AB., Agerholm, J. S., Villumsen, S., Kantsø, B., Bosnjak, E. & Nielsen, H. I. (2011). Zoonotic aspects of Coxiella burnetii antibody positivity between dairy cattle herds and their farmers. Abstract from International Meeting on Emerging Diseases and Surveillance, Wien, Austria.

Alstrup, A. K. O. (2013). Zoonoser i fodret – hvilke udfordringer har vi i Europa? Dansk Veterinærtidsskrift.

Alstrup, A. K. O. (2021). Zoonoser - i et overblik. Dansk Veterinærtidsskrift, 2021(1), 8-9.

Reimers, A., Helde, G., Becser Andersen, N., Aurlien, D., Surlien Navjord, E., Haggag, K., Christensen, J., Lillestølen, K. M., Nakken, K. O. & Brodtkorb, E. (2018). Zonisamide serum concentrations during pregnancy. Epilepsy Research, 144, 25-29. https://doi.org/10.1016/j.eplepsyres.2018.05.002

Stewart, L. (2002). Zoning in on music and the brain. Trends in Cognitive Sciences, 6(11), 451.

Lima, W., Parreira, K., Devuyst, O., Caplanusi, A., N´Kuli, F., Van Der Smissen, P., Alves, P., Verroust, P., Christensen, E. I., Terzi, F., Matter, K., Pierreux, M. & Courtoy, P. (2010). ZONAB is regulated during cell polarization and represses apical differentiation. Journal of the American Society of Nephrology, 21, 478-488.

Kiss, A., Søderman, A., Bundzikova, J., Pirnik, Z. & Mikkelsen, J. (2006). Zolpidem, a selective GABA(A) receptor alpha1 subunit agonist, induces comparable Fos expression in oxytocinergic neurons of the hypothalamic paraventricular and accessory but not supraoptic nuclei in the rat. Brain Research Bulletin, 71(1-3), 200-2007. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Citation&list_uids=17113947

Vegger, J. B., Brüel, A. & Thomsen, J. S. (2018). Zoledronic acid prevents disuse osteopenia and augments gene expression of osteoclastic differentiation markers in mice. Journal of Musculoskeletal and Neuronal Interactions, 18(2), 165-175.

Wendelboe, M. H., Thomsen, J. S., Henriksen, K., Vegger, J. B. & Brüel, A. (2016). Zoledronate prevents lactation induced bone loss and results in additional post-lactation bone mass in mice. Bone, 87, 27-36. https://doi.org/10.1016/j.bone.2016.03.012

Granild-Jensen, J. B., Møller-Madsen, B., Rackauskaite, G., Farholt, S., Søndergaard, C., Sørensen, T. H., Vestergaard, E. T. & Langdahl, B. L. (2023). Zoledronate increases bone mineral density in non-ambulant children with cerebral palsy: A randomized, controlled trial. Developmental Medicine and Child Neurology, 65(S2), 67. https://doi.org/10.1111/dmcn.15595

Granild-Jensen, J. B. (2022). Zoledronate increases bone mineral density in non-ambulant children with cerebral palsy: A randomized, controlled trial. Abstract from DNPS Årsmøde 2022, Middelfart, Denmark.

Granild-Jensen, J. B., Møller-Madsen, B., Rackauskaite, G., Farholt, S., Søndergaard, C., Sørensen, T. H., Vestergaard, E. T. & Langdahl, B. L. (2023). Zoledronate increases bone mineral density in non-ambulant children with cerebral palsy: A randomized, controlled trial. The Journal of Clinical Endocrinology & Metabolism, 108(11), 2840-2851. https://doi.org/10.1210/clinem/dgad299

Granild-Jensen, J. B., Møller-Madsen, B., Rackauskaite, G., Farholt, S., Søndergaard, C., Vestergaard, E. T. & Langdahl, B. L. (2023). Zoledronate increases Bone Mineral Density in children with severe cerebral palsy: A randomized, controlled trial. 91.

Sørensen, J. S., Sani, F., Flemming, P., Ellermann, A., Kurt, K., Kjærsgård, P. & Birkebæk, N. (2009). ZnT8, GAD 65 and IA-2 autoantibodies in type 1 diabetes children at diagnosis and 3-5 years after the diagnosis, stratified for residual beta cell function. Hormone Research, (Suppl 3), 53.

Sørensen, J. S., Vaziri-Sani, F., Pociot, F., Kristensen, K., Brorsson, C., Lyngssø, L., Dolmer, B. & Birkebæk, N. (2010). ZnT8 autoantibody specificities at, and 3-5 years after clinical onset, associates with the age at diagnosis and the SLC30A8 gene polymorphism in Danish children. Pediatric Diabetes, 11(Suppl 14):24.

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